Table 1.
Genetic diversity of Plasmodium falciparum parasite populations from pre-elimination settings in Southern Africa.
| Population | n | h | A ± SE | He ± SE | MOI ± SE | 1-Fws ± SE | LD |
|---|---|---|---|---|---|---|---|
| Eswatini | 835 | 817 | 13.3 ± 1.3 | 0.75 ± 0.03 | 2.32 ± 0.04 | 0.22 ± 0.01 | 0.17*** |
| South Africa | 747 | 740 | 12.2 ± 1.2 | 0.74 ± 0.03 | 2.13 ± 0.04 | 0.21 ± 0.01 | 0.14*** |
| Namibia | 2,585 | 2,576 | 17.3 ± 1.45 | 0.75 ± 0.03 | 2.74 ± 0.03 | 0.22 ± 0.01 | 0.212*** |
| Mozambique | 1,147 | 1,139 | 14.0 ± 1.38 | 0.74 ± 0.03 | 2.14 ± 0.03 | 0.24 ± 0.01 | 0.119*** |
| Total | 5,314 | 5,272 | 14.2 ± 1.3 | 0.75 ± 0.03 | 2.33 ± 0.03 | 0.22 ± 0.01 | 0.18*** |
n, number of isolates genotyped; h, number of haplotypes (or multilocus genotypes); A, mean number of alleles per locus; He, heterozygosity; MOI, multiplicity of infection; 1-Fws, outbreeding, LD, linkage diseqilibrium.
p ≤ 0.001 (Monte Carlo test, 1,000 permutations).