Table 3.

Frequencies estimates of SP-resistant haplotypes from the Cameroonian data.

Haplotype		Frequency p		Prevalence p		Cond. prevalence p		Ad-hoc freq. p
		Years		Years		Years		Years
dhfr	dhps	01/02	04/05	01/02	04/05	01/02	04/05	01/02	04/05
NCSI	SAKAA	0.0190	0.00468	0.0290	0.0070	0.0168	0.0037	0.0204	0.0063
NCSI	AAKAA	0.0604	0.00548	0.0905	0.0082	0.0521	0.0043	0.0476	0.0063
NCSI	SGKAA	0.0178	0.00965	0.0272	0.0144	0.0151	0.0075	0.0136	0.0063
ICNI	SGKAA	0.0164	< 10−12	0.0250	< 10−12	0.0194	< 10−12	0.0272	−−
NRNI	SAKAA	0.0095	0.01025	0.0145	0.0152	0.0084	0.0084	0.0136	0.0127
NRNI	AAKAA	0.0122	< 10−12	0.0188	< 10−12	0.0130	< 10−12	0.0136	−−
NRNI	SGKAA	0.0475	0.02179	0.0717	0.0322	0.0583	0.0257	0.0612	0.0253
NRNI	AGKAA	0.0134	0.00935	0.0205	0.0139	0.0124	0.0082	0.0204	0.0127
IRNI	SAKAA	0.0271	0.04085	0.0413	0.0600	0.0387	0.0564	0.0340	0.0506
IRNI	AAKAA	0.2447	0.25216	0.3372	0.3384	0.2493	0.2515	0.1973	0.2089
IRNI	SGKAA	0.3792	0.46288	0.4921	0.5698	0.4325	0.5202	0.3741	0.4494
IRNI	SAKAT	0.0265	0.00776	0.0404	0.0116	0.0230	0.0063	0.0204	0.0063
IRNI	AGKAA	0.0606	0.12062	0.0909	0.1711	0.0867	0.1714	0.0884	0.1519
IRNI	SGKAT	0.0165	< 10−12	0.0252	< 10−12	0.0198	< 10−12	0.0204	−−

The first column shows the amino acid sequence at codons 51, 59, 108, and 164 at the dhfr locus and the second column shows the amino acid sequence at codons 436, 437, 540, 581, and 613 at the dhps locus. A total of 50 and 36 haplotypes were estimated to have strictly positive frequency in 2001/2002 and 2004/2005, respectively. Only haplotypes with an estimated frequency >0.01 in 2001/2002 or 2004/2005 are reported. The remaining columns show the MLE of the respective frequencies, the estimated prevalence, the estimated conditional prevalence, and the ad-hoc estimate (relative unambiguous prevalence) for the haplotype frequencies. Cond., Conditional; Freq., Frequency.