Table 1.
Protein hits identified from Lysate CETSA
| PlasmoDB ID | Target name | Heat challenge (°C) | MDT (nM) |
|---|---|---|---|
| PF3D7_0513300 | Purine nucleoside phosphorylase | 55 | 1047.2 |
| 60 | 2425.8 | ||
| PF3D7_1358800 | 40S ribosomal protein S15 | 60 | 48,373.9 |
| PF3D7_0210100 | 60S ribosomal protein L37ae (putative) | 55 | 25,032.5 |
| PF3D7_0531100 | Conserved Plasmodium protein, unknown function | 55 | 4798.9 |
| PF3D7_1360800 | Falcilysin | 60 | 11,089.5 |
| PF3D7_1416500 | NADP-specific glutamate dehydrogenase | 60 | 29.8 |
Analysis was conducted at 50 °C, 55 °C, and 60 °C across 1906, 1787, and 1676 proteins, respectively.