Table 1. Estimated parameters affecting the size of the readily releasable pool (RRP).
Displayed is mean ± standard error of the mean (SEM). Two-sample t-test or Welch’s t-test comparing mutant to wildtype (WT): *p < 0.05; ***p < 0.001; ****p < 0.0001, #non-significant (p = 0.125), ¤non-significant (p = 0.210).
| Mean ± SEM | WT | V48F | WT | D166Y | Syt1 WT | Syt1 KO |
|---|---|---|---|---|---|---|
| k1 [vesicles/s] | 385.6 ±52.2 |
79.87*** ±12.5 |
457.4 ±77.4 |
37.68**** ±7.33 |
1227 ±189 |
646* ±114 |
|
k−1 [1/s] |
0.0903 ±0.0091 |
0.0605# ±0.011 |
0.1114 ±0.012 |
0.0294**** ±0.0122 |
0.140 ±0.016 |
0.114¤ ±0.013 |
|
kf [1/s] |
0.000844 ±0.000178 |
0.0164**** ±0.00230 |
0.000398 ±0.000077 |
0.03522**** ±0.00352 |
0.000235 ±0.000043 |
0.00286*** ±0.00062 |