Optimization for the synthesis of NH-1,2,3-triazoles 4^a.

Entry	Base	Yield 4ab (%)
1	Pyrrolidine	97
2	Piperidine	>99
3	Morpholine	84
4	Et3N	26
5	DBU	23
6	DABCO	10
7	TMG	47
8	TMEDA	6
9	Na2CO3	12
10	NaOH	27
11	Cs2CO3	33
12	K2CO3	24

^aReaction condition: 3a (0.1 mmol, 33.4 mg) and corresponding base (2 eq.) were dissolved in 1,4-dioxane (2 mL) and stirred at room temperature for 12 hours.

^bThe yield was determined by HPLC using pure 4a as external standard [t_3a = 2.937 min, λ_max = 245.2 nm, CH₃CN/water = 50 : 50 (v/v)].