Table 2.
Hazard ratio of any grade 3–5 chronic health condition for 583 2-year survivors of autologous BMT for lymphoma performed before age 40 years.
| All BMT recipients | Hodgkin lymphoma | Non-Hodgkin lymphoma | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Variable | HR | 95% CI | p value | HR | 95% CI | p value | HR | 95% CI | p value |
| Age at BMT (years) | |||||||||
| ≤21 | Ref | Ref | |||||||
| 22–30 | 1.46 | 0.79–2.72 | 0.23 | 1.22 | 0.61–2.43 | 0.58 | |||
| >30 | 2.31 | 1.27–4.19 | 0.01 | 2.16 | 1.12–4.18 | 0.02 | |||
| Race/ethnicity | |||||||||
| Non-Hispanic white | Ref | Ref | |||||||
| Black | 0.53 | 0.24–1.14 | 0.10 | 3.79 | 1.88–7.67 | 0.0002 | |||
| Hispanic | 1.59 | 0.91–2.79 | 0.11 | 1.50 | 0.88–2.56 | 0.14 | |||
| Other | 1.25 | 0.58–2.66 | 0.57 | 0.75 | 0.25–2.29 | 0.61 | |||
| Year of BMT | |||||||||
| <1990 | Ref | Ref | |||||||
| 1990–1999 | 0.73 | 0.48–1.09 | 0.13 | 0.58 | 0.32–1.06 | 0.08 | |||
| ≥2000 | 0.54 | 0.34–0.85 | 0.01 | 0.34 | 0.18–0.64 | 0.001 | |||
| Stem cell source | |||||||||
| Bone marrow | Ref | ||||||||
| PBSC | 0.66 | 0.42–1.05 | 0.08 | ||||||
| Pre-BMT radiotherapy | |||||||||
| No | Ref | Ref | Ref | ||||||
| Yes | 1.52 | 1.13–2.03 | 0.01 | 1.47 | 1.00–2.18 | 0.05 | 1.77 | 1.13–2.76 | 0.01 |