Table 2.
Univariate analysis to assess the impact of marital status on OS/CSS in PDAC.
| Variables | OS | CSS | ||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Sex | ||||
| Male | Reference | Reference | ||
| Female | 0.952 (0.928–0.977) | < 0.001 | 0.958 (0.932–0.984) | 0.002 |
| Age at diagnosis | ||||
| < 50 years | Reference | Reference | ||
| ≥ 50 years | 1.139 (1.078–1.203) | < 0.001 | 1.095 (1.036–1.158) | 0.001 |
| Race | ||||
| White | Reference | Reference | ||
| Black | 1.121 (1.074–1.170) | < 0.001 | 1.103 (1.055–1.153) | < 0.001 |
| American Indian/Alaska native | 1.213 (1.005–1.464) | 0.045 | 1.252 (1.035–1.516) | 0.021 |
| Asian or Pacific Islander | 0.966 (0.919–1.016) | 0.178 | 0.980 (0.931–1.031) | 0.432 |
| Grade | ||||
| Well differentiated | Reference | Reference | ||
| Moderately differentiated | 1.130 (1.080–1.181) | < 0.001 | 1.145 (1.093–1.200) | < 0.001 |
| Poorly differentiated | 1.590 (1.520–1.664) | < 0.001 | 1.629 (1.554–1.707) | < 0.001 |
| Undifferentiated | 1.753 (1.558–1.972) | < 0.001 | 1.801 (1.586–2.034) | < 0.001 |
| TNM stage (6th) | ||||
| I | Reference | Reference | ||
| II | 1.336 (1.267–1.408) | < 0.001 | 1.411 (1.333–1.493) | < 0.001 |
| III | 2.277 (2.134–2.430) | < 0.001 | 2.472 (2.308–2.648) | < 0.001 |
| IV | 4.003 (3.786–4.232) | < 0.001 | 4.391 (4.138–4.660) | < 0.001 |
| Surgery | ||||
| No | Reference | Reference | ||
| Yes | 0.315 (0.306–0.324) | < 0.001 | 0.303 (0.294–0.312) | < 0.001 |
| Marital status | ||||
| Unmarried | Reference | Reference | ||
| Married | 0.842 (0.820–0.865) | < 0.001 | 0.852 (0.829–0.876) | < 0.001 |