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. 2024 Mar 4;81(1):115. doi: 10.1007/s00018-024-05126-1

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — Hepatic expression of YAP and TAZ in healthy, regenerating, and fibrotic liver tissues. A Immunohistochemical stains of murine YAP and TAZ in healthy liver tissues of 10-week-old mice. Arrowheads: BECs/bile ducts, arrows: sinusoidal cells. B Staining of YAP and TAZ after 70% PHx. Samples were collected at different stages of hepatic regeneration: 2 days (proliferation), 4 days (reorganization), and 9 days (termination). Arrowheads: BECs/bile ducts. C Immunohistochemical stains of YAP and TAZ in CCl₄-induced liver fibrosis. Ten-week-old mice were treated with CCl₄ for six weeks followed by four weeks without injections. Arrowheads: BECs/bile ducts