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. 2024 Jan 9;130(5):861–868. doi: 10.1038/s41416-023-02560-z

Table 2.

Percent sensitivity of serum biomarkers for benign disease and for early stage (I-II) and late stage (III-IV) ovarian cancer at 98% specificity in healthy controls evaluated in the EDRN validation serum set.

Ag/AAb Biomarker/Sensitivity (%) Benign Early Late All cases
TP53 (RAPID) 0.5 12.5 25.3 22.0
IL-8 8.5 26.5 15.6 18.4
CTAG1 3.0 7.9 19.4 16.4
AAb
HE4 Ag-AAb 3.0 18.8 8.6 11.2
CA125 22.0 62.5 93.5 85.6
HE4 0.0 40.6 86.0 74.4
Ag OPN 4.0 12.5 22.6 20.0
HK 6 1.0 6.3 46.7 36.3
HK10 2.0 9.4 49.5 39.2