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. 2024 Mar 4;14:5365. doi: 10.1038/s41598-024-55320-1

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Cell-mediated immunity. IFN-γ response was measured in the modified Intent-to-Treat population by ELISpot. Mean of Spot Forming Cell (SFC) counts per 10⁶ cells ± 95% Confidence Interval (CI) are represented. † Indicates statistically significant (p ≤ 0.0001) differences from all other treatment-matched time. The p values for all the other comparisons are presented as within group values at each timepoint or between group values across timepoints (paired t-test on log-transformed values, SAS).