Table 2.
Baseline study eye characteristics (intent-to-treat population)
| SE-implant (N = 197) | FE-implant (N = 200) | Timolol (N = 193) | Total (N = 590) | |
|---|---|---|---|---|
| Diagnosis | ||||
| Open-angle glaucoma (OAG)a | 170 (86.3) | 175 (87.5) | 167 (86.5) | 512 (86.8) |
| Ocular hypertension (OHT) | 27 (13.7) | 25 (12.5) | 26 (13.5) | 78 (13.2) |
| Number of glaucoma medication classes used at screening, n (%) | ||||
| 0 | 54 (27.4) | 43 (21.5) | 46 (23.8) | 143 (24.2) |
| 1 | 99 (50.3) | 116 (58.0) | 100 (51.8) | 315 (53.4) |
| 2 | 38 (19.3) | 37 (18.5) | 41 (21.2) | 116 (19.7) |
| 3 | 6 (3.0) | 4 (2.0) | 6 (3.1) | 16 (2.7) |
| Screening IOP (mmHg) | ||||
| Mean (SD) | 19.77 (4.46) | 19.52 (4.50) | 19.67 (4.35) | 19.66 (4.43) |
| Mean (SD) IOP (mmHg) at baseline | ||||
| 8 a.m. | 24.37 (3.25) | 24.72 (3.40) | 24.72 (3.51) | 24.60 (3.39) |
| 10 a.m. | 24.09 (3.32) | 24.27 (3.27) | 24.03 (3.10) | 24.13 (3.23) |
| 4 p.m. | 23.59 (3.15) | 23.57 (3.14) | 23.61 (3.17) | 23.59 (3.15) |
| Iris color, n (%) | ||||
| Blue | 41 (20.8) | 57 (28.5) | 55 (28.5) | 153 (25.9) |
| Brown | 122 (61.9) | 109 (54.5) | 106 (54.9) | 337 (57.1) |
| Green | 7 (3.6) | 7 (3.5) | 7 (3.6) | 21 (3.6) |
| Hazel | 27 (13.7) | 26 (13.0) | 25 (13.0) | 78 (13.2) |
| Other | 0 | 1 (0.5) | 0 | 1 (0.2) |
FE-implant fast-eluting travoprost intracameral implant, IOP intraocular pressure, OAG open-angle glaucoma, OHT ocular hypertension, SD standard deviation, SE-implant slow-eluting travoprost intracameral implant
aOpen-angle glaucoma included juvenile, primary, pigmentary, and pseudoexfoliative