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. 2024 Mar 4;15:1975. doi: 10.1038/s41467-024-46250-7

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 6 — a Schematic representation of LNP formulation and delivery to cells in various organs of Ai14 mice. 3D visualization of a liver endothelial cell with (b) and without (c) the expression of tdTomato. 3D visualization of a spleen immune cell with (d) and without (e) the expression of tdTomato. 3D visualization of a lung endothelial cell with (f) and without (g) the expression of tdTomato. h Bar plot illustrating the percentage of tdTomato+ expression of 79.41%, 13.45%, and 11.39%, respectively, for liver (n = 102), spleen (n = 316), and lung (n = 119) cells. Source data are provided as a Source Data file.