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. 2024 Mar 4;15:1977. doi: 10.1038/s41467-024-46085-2

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — A Per CpG DNA methylation levels (mCG) and CpG observed/expected content for eight metazoan genomes. Global mCG levels obtained from publicly available WGBS datasets^6,107,108. B Genomic and mitochondrial mean mCG levels (n = 2 biological replicates). Error bars represent standard error of the mean (SEM). C Browser track depicting mCG profiles. mCG values represented in this figure correspond to merged WGBS replicates. D Total genomic mCH levels (%).