Fig. 2. Potential screening methods for identifying efficacious repurposed drugs.

These methods may either be in vitro or in vivo studies, and may include drug-based phenotypic screens, target-based high throughput assays. Alternatively, computational or virtual screening (in silico) may be done through signature matching (using –omics data), AI or machine and deep learning, genome-wide association studies and disease/target association studies, or chemical similarity and molecular docking simulations. Created using Biorender, February 2023.