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. 2024 Mar 4;14:5345. doi: 10.1038/s41598-024-55936-3

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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(A): Boxplot illustrating the distribution of trPC2—Inverted Acute Index—stratified by Active Rejection status by pathology diagnosis. Dunn's test was used for pairwise statistical comparisons. (B): Principal Component Analysis displaying interaction of the Inverted Acute and Chronicity Indices, computed for the external set along with reciprocal serum creatinine indicators (rSCs and rSC), n = 44. The extracted principal components include the renal function loadings, therefore, are labeled as rfPC1 and rfPC2.