. 2024 Mar 4;14:5345. doi: 10.1038/s41598-024-55936-3

Table 2.

Detailed list of variables, along with their mathematical formulas and definitions, used in the quantitative analysis of renal cortical tissue.

Variable	Formula	Definition
CTA	$\begin{matrix} = b i o p s y a r e a - g l o m e r u l i a r e a - a r t e r i e s a r e a \\ = t u b u l a r l u m e n a r e a + t u b u l a r c e l l a r e a \\ + p e r i t u b u l a r c a p i l l a r i e s a r e a \\ + f i b r i l l a r y c o l l o g e n a r e a \\ + n o n - f i b r i l l a r y m a t r i x a r e a \end{matrix}$	Cortical tubulointerstitial area
tLumen%	$= \frac{t u b u l a r l u m e n a r e a}{CTA} \times 100$	Percentage of tubular lumen area
tCell%	$= \frac{t u b u l a r c e l l a r e a}{CTA} \times 100$	Percentage of tubular cells area
ptc%	$= \frac{p e r i t u b u l a r c a p i l l a r i e s a r e a}{CTA} \times 100$	Percentage of peritubular capillaries area
iColl%	$= \frac{f i b r i l l a r y c o l l a g e n a r e a}{CTA} \times 100$	Percentage of fibrillary collagen area
iMatrix%	$= \frac{n o n - f i b r i l l a r y m a t r i x a r e a}{CTA} \times 100$	Percentage of non-fibrillary matrix area
tSize	$= \frac{t u b u l a r l u m e n a r e a + t u b u l a r c e l l s a r e a}{CTA} \times 100$	Mean area of tubules
tCellden	$= \frac{N (cells)}{t u b u l a r a r e a} \times 100$	Densities of cells in tubules

The table includes metrics related to tubular structure, peritubular capillaries, and matrix components, all calculated relative to the Cortical Tubulointerstitial Area (CTA).