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DNA methylation abrogates the NRF1-mediated suppression of the promoter P1 activity. DF1 cells were co-transfected with either pCMV-HA-NRF1 or pCMV-HA, along with unmethylated or methylated P1 reporter as well as pRL-TK as an internal control. All data are presented as the mean ± SEM, *p < 0.05.
