In vitro α-amylase and α-glucosidase inhibitory potential of compounds 5a–i.
| Compound | IC50 (μM) | |
|---|---|---|
| α-Amylase | α-Glucosidase | |
| 5a | >125 | 41.9 ± 0.78 |
| 5b | >125 | 46.6 ± 0.1 |
| 5c | >125 | 15.2 ± 0.3 |
| 5d | >125 | 54.9 ± 0.9 |
| 5e | 121.2 ± 1.4 | 42.8 ± 0.2 |
| 5f | 42.1 ± 0.2 | >125 |
| 5g | >125 | >125 |
| 5h | 16.4 ± 0.1 | 31.6 ± 0.4 |
| 5i | 34.4 ± 0.36 | 66.9 ± 0.5 |
| Acarbose | 24.0 ± 0.9 | 49.3 ± 1.1 |