Key binding interactions of compounds 5c and 5h with α-glucosidase protein.
| Protein | Compound | Protein residue | Interaction unit of compounds | Type of interaction |
|---|---|---|---|---|
| α-Glucosidase (3TOP) | 5c | ARG1311 | –NO2 | H-Bond |
| ASN1792 | N of isoxazole | H-Bond | ||
| ARG1730 | Quinoxaline, isoxazole | π–alkyl | ||
| ARG1311 | –NO2 | H-Bond | ||
| 5h | ASN1792 | O of isoxazole | Carbon H-bond | |
| ARG1311 | Phenyl | π–alkyl | ||
| TYR1787 | O of isoxazole | H-Bond | ||
| HIS1727 | Quinoxaline | π–π T-shaped | ||
| LEU1794 | –Cl | π–alkyl | ||
| ARG1730 | Quinoxaline, isoxazole | π–alkyl |