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. 2024 Mar 5;14(11):7779–7785. doi: 10.1039/d3ra07835c

Vitek 2 identification of three isolates (MSK4, MSK7 and MSK9) according to the CLSI/EUCAST guidelinea.

Antimicrobial MSK4 (MIC) Interpretation MSK7 (MIC) Interpretation MSK9 (MIC) Interpretation
β-lactam Ampicillin ≥32 R ≥32 R ≥32 R
β-lactam+ β-lactamase inhibitor Piperacillin/tazobactam ≥128 R ≥128 R ≥128 R
Amoxicillin/clavulanic acid ≥32 R ≥32 R ≥32 R
Cephalosporin Cefepime ≥64 R 32 R 32 R
Cefoperazone/sulbactam ≥64 R ≥32 *R ≥64 R
Ceftriaxone ≥64 R ≥64 R ≥64 R
Cefuroxime ≥64 R ≥64 R ≥64 R
Cefuroxime axetil ≥64 R ≥64 R ≥64 R
Carbapenem Meropenem ≥16 R 8 R 8 R
Imipenem 8 R ≤0.25* *I ≤0.25* *I
Ertapenem ≥8 R 4 R ≥8 R
Aminoglycosides Amikacin ≥64 R ≥64 R ≥64 R
Gentamicin ≥16 R ≥16 R ≥16 R
Fluroquinolone Ciprofloxacin ≥4 R ≥4 R ≥8 R
Nalidixic acid ≥32 R ≥32 R ≥32 R
Nitrofuran Nitrofurantoin 128 R 64 I 128 R
Polymyxin Colistin ≥16 R ≥8 R ≥16 R
Folate pathway Trimethoprim/sulfamethoxazole ≤20 S ≥320 R ≥320 R
Glycylcyclines Tigecycline 2 S ≤0.5 S 2 S
a

S: susceptible; I: intermediate; R: resistant; MIC: minimum inhibitory concentration.