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. 2024 Mar 5;17(3):e13727. doi: 10.1111/cts.13727

TABLE 2.

ΔΔQTcF in ms (QT/QTc population).

Timepoint postdose (h) Statistics Rimegepant 75 mg Rimegepant 300 mg Moxifloxacin 400 mg
0.5 LS mean 1.2 −0.1 8.1
90% CI (−1.05, 3.38) (−2.29, 2.12) (5.90, 10.37)
1.0 LS mean 0.6 0.1 11.6
90% CI (−1.58, 2.80) (−2.07, 2.27) (9.37, 13.78)
1.5 LS mean −0.7 0.9 12.0
90% CI (−2.54, 1.22) (−0.94, 2.79) (10.10, 13.89)
2 LS mean −1.4 −0.5 12.8
90% CI (−3.39, 0.55) (−2.44, 1.47) (10.80, 14.78)
2.5 LS mean −0.2 0.5 12.8
90% CI (−2.42, 2.06) (−1.72, 2.72) (10.50, 15.00)
3 LS mean 0.5 0.7 13.3
90% CI (−1.62, 2.54) (−1.33, 2.79) (11.23, 15.42)
3.5 LS mean 2.0 1.1 14.1
90% CI (0.01, 4.06) (−0.87, 3.16) (12.10, 16.20)
4 LS mean 1.0 0.9 13.5
90% CI (−1.16, 3.10) (−1.26, 2.98) (11.33, 15.64)
5 LS mean 0.9 1.5 11.1
90% CI (−2.27, 4.15) (−1.66, 4.69) (7.88, 14.32)
6 LS mean 1.2 0.9 9.4
90% CI (−1.86, 4.27) (−2.17, 3.92) (6.27, 12.47)
12 LS mean −0.3 −0.9 7.5
90% CI (−2.85, 2.30) (−3.44, 1.68) (4.89, 10.10)
24 LS mean 0.9 1.6 6.7
90% CI (−1.51, 3.31) (−0.80, 3.98) (4.23, 9.10)

Abbreviations: CI, confidence interval; LS, least squares; ΔΔQTcF, placebo‐corrected change‐from‐baseline in Fridericia corrected QT interval.