Table 3.

Cardiac phenotypes for the four sequenced individuals obtained from a 12-lead electrocardiogram.

	I (male)	II (male)	III (female)	IV (male)	Normal range
Heart rate	60 bpm	55 bpm	75 bpm	56 bpm	60 - 100 bpm
QRS interval	102 ms	108 ms	90 ms	98 ms	80-120 ms
Sinus rhythm	Yes	Yes	Yes	Yes
QTc interval	392 ms	400 ms	350 ms	400 ms	see below1
PQ interval	243 ms	184 ms	142 ms	180 ms
P wave	118 ms	143 ms	120 ms	94 ms
RR	996 ms	1040 ms	786 ms	1054
ST segment abnormalities	None	None	None	None	No abnormalities
Pathological Q wave	None	Yes	None	None	No abnormalities
Sokolow-Lyon-Index	1.55 mV	2.20 mV	2.20 mV	2.17 mV	< 3.5 mV
Summary	Normal	Q wave and negative T in III – presence of coronary heart disease	Normal	Normal

Bpm, beats per minute; ms, milliseconds.

¹An “abnormal” QTc in males is a QTc above 450 ms; and, in females, above 470 ms.