Table 1. Single cell studies discussed in this review.
Single cell RNA sequencing (scRNA), single cell whole genome sequencing (scWGS), single-cell sequencing Assay for Transposase-Accessible Chromatin (scATAC), single-cell DNA methylome sequencing (scDNAme), single nucleus RNA sequencing (snRNA), Cytometry by Time of Flight (CyTOF), Cellular Indexing of Transcriptomes and Epitopes (CITE).
| Reference | Assay | Organism | Tissue type | Details | Accession |
|---|---|---|---|---|---|
| Larsson et al [7] | scRNA | human | cell line | U3065MG | E-MTAB-9296, E-MTAB-10615 |
| Abdelfattah et al [12] | scRNA | human | tumor | LGG, pGBM, rGBM | GSE182109 |
| LeBlanc et al [13] | scRNA, scWGS | human | tumor, explants, cell lines | pGBM | GSE173280 |
| Jacob et al [14] | scRNA | human | tumor, organoids | pGBM, rGBM | GSE141946 |
| Patel et al [18] | scRNA | human | CD45− tumor, cell lines | pGBM | GSE57872 |
| Wang et al [19] | scRNA | human | tumor | pGBM, rGBM | EGAS00001001033 |
| Neftel et al [20] | scRNA | human | CD45− tumor | adult, pediatric GBM | GSE131928 |
| Liu et al [21] | scRNA, scATAC | human | tumor | DMG | GSE184357 |
| Couturier et al [23] | scRNA | human | tumor, GSCs, normal | GBM | EGAS00001004422 |
| Yuan et al [26] | scRNA | human | tumor | pGBM, rGBM | GSE103224 |
| Müller et al [27] | scRNA | human | tumor | pGBM | EGAS00001001900 |
| Wu et al [31] | scRNA | human | tumor | multifocal GBM | HRA002913, HRA002914 |
| Yu et al [32] | scRNA | human | tumor | WHO grade II - IV | HRA000179 |
| Darmanis et al [33] | scRNA | human | tumor, peritumor | pGBM | GSE84465 |
| Johnson et al [37] | scRNA, scDNAme | human | tumor | pGBM, rGBM | EGAS00001005300 |
| Bhaduri et al [39] | scRNA, snRNA | human | tumor, PTPRZ1+ tumor, normal | GBM | PRJNA579593, SRP132816 |
| Richards et al [40] | scRNA, snRNA | human | GSCs | pGBM, rGBM | EGAS00001004656 |
| Wang et al [47] | scRNA, snRNA, scATAC | human | tumor | pGBM | EGAS00001003845 |
| Guilhamon et al [48] | scATAC | human | tumor | pGBM | GSE139136 |
| Wang et al [49] | snRNA, scATAC | human | tumor | pGBM, rGBM | EGAS00001004909 |
| Müller et al [54] | scRNA | human | tumor, CD11b+ | pGBM, LGG | EGAS00001002185 |
| Goswami et al [65] | scRNA, CyTOF | human | CD45+ tumor | pGBM | PRJNA588461 |
| Chen et al [66] | scRNA | human | tumor | GBM | GSE141383 |
| Mathewson et al [77] | scRNA | human | T-cells tumor | pGBM, rGBM | GSE163108 |
| Ravi et al [78] | scRNA | human | CD45+ CD3+ tumor | pGBM | DOI 10.17605/OSF.IO/4Q32E |
| Jain et al [86] | scRNA | human | CAFs tumor | pGBM | GSE132825 |
| Xie et al [88] | scRNA | human | CD31+ tumor & peritumor | pGBM | GSE162631 |
| Jessa et al [34] | scRNA | human, mouse | tumor, normal | non-GBM | EGAS00001003368, GSE133531 |
| Pombo Antunes et al [57] | scRNA, CITE | human, mouse | CD45+ tumor | pGBM, rGBM; orthotopic | GSE163120 |
| Zamler et al [61] | scRNA | human, mouse | CD45+ tumor | GEMM, orthotopic | GSE147275 |
| Yeo et al [38] | scRNA | mouse | CD45− & CD45+ tumor | GEMM | GSE196175 |
| Van Hove et al [55] | scRNA | mouse | CD45+ normal | WT, GEMM | GSE128855 |
| Hammond et al [56] | scRNA | mouse | CD45+ CD11b+ Cx3cr1+ normal | Microglia | GSE121654 |
| Yeini et al [60] | scRNA | mouse | CD11b+, CD45+ CD11b− tumor | orthotopic | GSE156663 |
| Rajendran et al [63] | scRNA | mouse | CD45+ tumor | non tumor, LGG, HGG | GSE221440 |
| Sawant et al [79] | scRNA | mouse | Tregs tumor | GEMM | GSE126184 |