Table 4.
The models of predictors in the variability of RdRp gene of SARS-CoV-2 based on the logistic regression analysis
| Model | Modeling to | Variable (reference variant) | LR | OR (95% Cl) | p-value |
|---|---|---|---|---|---|
| A | Female | Constant term | −1.003 | 0.367 (0.147–0.913) | 0.031 |
| Number of mutations | 0.276 | 1.318 (1.013–1.715) | 0.041 | ||
| B | > 1 mutation | Constant term | −2.832 | 0.059 (0.015–0.232) | < 0.001 |
| Spectrum of COVID-19 | 0.811 | 0.250 (1.129–4.486) | 0.021 | ||
| C | > 2 mutations | Constant term | −4.302 | 0.014 (0.002–0.104) | < 0.001 |
| Spectrum of COVID-19 | 0.968 | 2.633 (1.451–4.778) | 0.001 | ||
| Age | 0.037 | 2.633 (1.002–1.075) | 0.041 | ||
| D | Hospitalized | Constant term | −6.118 | 0.002 (0.000–0.049) | < 0.001 |
| 15279C > T | 3.210 | 24.788 (3.906–157.302) | < 0.001 | ||
| Age | 0.105 | 1.111 (1.050–1.176) | < 0.001 | ||
| E | > 48 years old | Constant term | −0.938 | 0.391 (0.181–0.846) | 0,017 |
| 15240C > T | −1.259 | 0.284 (0.090–0.897) | 0,032 | ||
| 15,096 T > C | 2.154 | 8.615 (1.032–71.936) | 0.047 | ||
| Hospitalized | 2.603 | 13.508 (4.423–41.254) | < 0,001 | ||
| Spectrum of COVID-19 | 1.287 | 3.623 (2.009–6.534) | < 0,001 |
The variables - number of mutations, specific mutation, age, gender, spectrum of COVID-19 (1st, 2nd, 3rd, 4th), hospitalized patients, outpatients) were used for the analysis. LR Estimate of the logistic regression parameter