Table 2.
Characteristics between matched septic patients with and without ARDS
| Variables | Non-ARDS group n = 737 | ARDS group n = 737 |
p- value | Standardized difference (%) |
|---|---|---|---|---|
| Male, n (%) | 445 (60.4) | 456 (61.9) | 0.557 | 0.1 |
| Age, median (IQR), years | 62 (48–75) | 64 (48–77) | 0.204 | 0.1 |
| BMI, median (IQR), kg/m2 | 22.9 (20.8–24.9) | 22.9 (20.9–25.1) | 0.686 | 2.5 |
| Chronic comorbidities, n (%) | ||||
| COPD/asthma | 32 (4.3) | 33 (4.5) | 0.899 | 5.0 |
| Cardiovascular disease | 121 (16.4) | 128 (17.4) | 0.627 | 4.6 |
| Hypertension | 237 (32.2) | 241 (32.7) | 0.824 | 2.3 |
| Diabetes | 149 (20.2) | 145 (19.7) | 0.794 | 2.1 |
| Cancer | 77 (10.5) | 65 (8.8) | 0.289 | 8.5 |
| CKD | 41 (5.6) | 48 (6.5) | 0.444 | 7.4 |
| Chronic liver disease | 9 (1.2) | 7 (1.0) | 0.817 | 6.4 |
| APACHE II score, median (IQR) | 17 (12–23) | 18 (13–23) | 0.090 | 10.5 |
| SOFA score, median (IQR) | 6 (3–9) | 7 (4–9) | 0.058 | 21.8 |
| Mechanical ventilation, n (%) | 527 (71.5) | 539 (73.1) | 0.485 | 2.3 |
| RRT, n (%) | 112 (15.2) | 124 (16.8) | 0.394 | 2.9 |
| Septic shock, n (%) | 336 (45.6) | 340 (46.1) | 0.834 | 12.6 |
| MAP, median (IQR), mmHg | 74 (60–88) | 75 (62–88) | 0.787 | 1.5 |
Abbreviations: ARDS, acute respiratory distress syndrome; BMI, body mass index; COPD, chronic obstructive pulmonary disease; CKD, chronic kidney disease; APACHE II, acute physiologic and chronic health evaluation II; SOFA, sequential organ failure assessment; RRT, renal replacement therapy; MAP, mean arterial pressure