TABLE 2.

Minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) of tdAMP-1 and tdAMP-2 against the indicated strain^a

Strain	Antibiotics	MIC (µg/mL)	MBC (µg/mL)
S. Typhi	tdAMP-1	32	64
	tdAMP-2	16	32
	tdAMP-3	ND	ND
	tdAMP-4	ND	ND
	Ciprofloxacin	0.004	0.016
	Melittin	16	64
S. Typhi gyrA S83F	tdAMP-1	32	64
	tdAMP-2	16	32
	Ciprofloxacin	0.125	0.5
Acapsular S. Typhi (∆tviBC)	tdAMP-1	32	64
	tdAMP-2	16	32
Hypercapsular S. Typhi (tviE P263S)	tdAMP-1	32–64	64
	tdAMP-2	32	32
S. Typhimurium LT2	tdAMP-1	32–64	64
	tdAMP-2	32–64	64
Uropathogenic E. coli CI5	tdAMP-1	64	64
	tdAMP-2	32–64	32–64
Uropathogenic E. coli J96	tdAMP-1	64	64
	tdAMP-2	32	64

^a Note that N-minimal medium was used in this study. ND, not determined.