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. 2024 Jan 19;12(3):e03226-23. doi: 10.1128/spectrum.03226-23

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Copyright © 2024 Zhou et al.

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Fig 10 — L-Serine was found to inhibit the inflammation levels caused by A. baumannii by upregulating SIRT1 in Beas 2B cells. (A and B) L-Serine regulates NLRP3, ASC, and caspase-1 at both protein and mRNA levels. (C) The effect of L-serine on mRNA levels of IL-18 and IL-1β induced by A. baumannii. (D) The effect of L-serine on the production of IL-18 and IL-1β caused by A. baumannii was measured by ELISA. ^*,#,▲P < 0.05. ^**,##,▲▲P < 0.01. ^{***,###,▲▲▲}P < 0.001. ^*Compared with the control group. ^#Compared with the A. baumannii group. ^▲Compared with the A. baumannii+L-serine group.