FIG. 9.

Summary of the interactions elucidated by the corepressor complex. Schematic representations of mSin3A (top) and SMRT (bottom) are shown. Arrows indicate the domains of each protein that mediate observable interactions with the domains of the other and/or with TFIIB. Also depicted are the locations of the domains of these proteins that can mediate transcriptional repression when expressed as GAL4-DBD fusions (SD-A and -B in mSin3A and SD-1 and -2 in SMRT). Numbers above or below each schematic refer to the relevant amino acid positions.