. 2024 Mar 4;13:13. doi: 10.1186/s13741-024-00369-9

Table 3.

Comparison of intraoperative hypotension and acute kidney injury in the single-arm trial versus contemporaneous comparison group

	Contemporaneous comparison N = 15,796	Trial N = 457	Crude model^b	Inverse probability of treatment weighing propensity model
Duration of Hypotension (MAP < 65)^a	15 [5, 39]	9 [3, 20]	− 0.31 (− 0.39 to − 0.22)	< 0.001	− 0.35 (− 0.43 to − 0.27)	< 0.001
Acute kidney injury	1898/12,421 (15.3%)	45/325 (13.8%)	0.93 (0.67 to 1.27)	0.674	0.91 (0.63 to 1.33)	0.637

Contemporaneous
comparison
N = 15,796

Trial
N = 457

Crude model^b

Inverse probability of treatment weighing propensity model

Effect Estimate^c
(95% CI)

P-Value

Effect estimate^c
(95% CI)

P value

Duration of Hypotension

(MAP < 65)^a

15 [5, 39]

9 [3, 20]

− 0.31 (− 0.39 to − 0.22)

< 0.001

− 0.35 (− 0.43 to − 0.27)

< 0.001

Acute kidney injury

1898/12,421 (15.3%)

45/325 (13.8%)

0.93 (0.67 to 1.27)

0.674

0.91 (0.63 to 1.33)

0.637

CI confidence interval: MAP mean arterial blood pressure)

Data is presented as median [quartile 1, quartile 3] in minutes, or n (%) depending on descriptive statistics

^aData is only available for 15,749 observations

^bAll models are adjusting for time in which blood pressure is measured (i.e., time at risk)

^cEffect estimates for hypotension are reported as exponentiated beta coefficients, whereas effect estimates for acute kidney injury are reported as odds ratios