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Functions of glycolysis and mitochondrial ATP generation during synaptic function. Energy-demanding processes depicted are (i) glycolysis-powered vesicle transport along microtubules, (ii) energy supply for the Na+/K+ ATPase by glycolysis, (iii) tethering of mitochondria at synapses, (iv) Glut4 exocytosis at active synapses and (v) endocytic vesicle blocked on ATP depletion.
