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. Author manuscript; available in PMC: 2024 Mar 5.
Published in final edited form as: Ann Neurol. 2023 Aug 12;94(4):798–802. doi: 10.1002/ana.26750

FIGURE 1:

FIGURE 1:

Quantification of HIV pol DNA in human brain regions. HIV pol DNA was quantified in fresh frozen FWM (blue), BG (red), and CBM ( purple) tissue from VS (n = 16) and untreated PWH (viremic; n = 21) or HIV-seronegative controls (HIV-; n = 2) by ddPCR. HIV pol DNA copies standardized to 106 cell equivalents. Median and IQRs shown. Comparisons made using non-parametric Mann–Whitney U tests. *p < 0.05. BG = basal ganglia; CBM = cerebellum; ddPCR = droplet digital polymerase chain reaction; FWM = frontal white matter; IQR = interquartile range; PWH = people with HIV; VS = virally suppressed.