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. Author manuscript; available in PMC: 2025 Mar 1.
Published in final edited form as: Mayo Clin Proc. 2024 Mar;99(3):437–444. doi: 10.1016/j.mayocp.2023.11.007

TABLE 1.

Population, All-Cause Deaths, Standardized Mortality Rates, and Mortality Rate Ratios By Demographic and Clinical Characteristics

Characteristic 2019 2020 Mortality Rate Ratio (95% CI) 2020 vs 2019 P value 2021 Mortality Rate Ratio (95% CI) 2021 vs 2019 P value
Populationa All-cause deaths Mortality rate per 100,000 person-years (95% CI) Populationb All-cause deaths Mortality rate per 100,000 person-years (95% CI) Populationc All-cause deaths Mortality rate per 100,000 person-years (95% CI)
Total 245414 2885 905 (871–939) 264448 3233 992 (957–1026) 1.10 (1.04–1.15) <0.001 271959 3151 945 (911–978) 1.04 (0.99–1.1) 0.096
Sex
 Males 113350 1461 1084 (1028–1140) 126224 1617 1148 (1091–1204) 1.06 (0.99–1.14) 0.114 130111 1627 1128 (1073–1184) 1.04 (0.97–1.12) 0.270
 Females 132064 1424 763 (722–804) 138224 1616 865 (822–909) 1.13 (1.10–1.22) 0.001 141848 1524 803 (762–844) 1.05 (1–1.13) 0.163
Age (January 1st of the year)
 18–39 93109 81 91 (71–111) 103202 112 111 (90–132) 1.22 (0.92–1.62) 0.174 106254 130 124 (103–146) 1.36 (1.03–1.80) 0.028
 40–49 35007 72 208 (160–256) 38972 85 219 (172–265) 1.05 (0.77–1.44) 0.752 40193 82 204 (160–249) 0.98 (0.72–1.35) 0.913
 50–59 40244 191 479 (411–547) 41653 204 490 (423–557) 1.02 (0.84–1.25) 0.825 41782 207 496 (428–563) 1.03 (0.85–1.26) 0.739
 60–69 37592 373 991 (890–1091) 39949 420 1046 (946–1146) 1.06 (0.92–1.21) 0.446 41660 446 1065 (967–1164) 1.08 (0.94–1.23) 0.299
 70–79 23432 561 2377 (2180–2573) 24494 664 2697 (2492–2903) 1.13 (1.01–1.27) 0.027 25699 650 2514 (2321–2708) 1.06 (0.94–1.18) 0.329
 80+ 16030 1607 9981 (9491–10471) 16178 1748 10757 (10250–11263) 1.08 (1.01–1.15) 0.030 16371 1636 9910 (9427–10392) 0.99 (0.93–1.06) 0.839
Age groups
 18–64 188770 516 279 (254–303) 205571 599 294 (270–317) 1.05 (0.94–1.19) 0.385 210807 627 299 (276–323) 1.07 (0.96–1.21) 0.228
 65+ 56644 2369 4171 (4003–4339) 58877 2634 4466 (4295–4637) 1.07 (1.01–1.13) 0.016 61152 2524 4111 (3950–4272) 0.99 (0.93–1.04) 0.610
Race
 White 212305 2721 905 (870–940) 228005 3022 979 (943–1015) 1.08 (1.03–1.14) 0.003 232660 2942 935 (901–970) 1.03 (0.98–1.09) 0.209
 African American 9267 49 937 (620–1253) 10826 66 1201 (854–1548) 1.28 (0.89–1.86) 0.187 11641 63 1034 (734–1334) 1.10 (0.76–1.60) 0.605
 Other/Unknown 23842 115 753 (611–896) 25617 145 1021 (840–1202) 1.36 (1.06–1.73) 0.015 27658 146 941 (772–1111) 1.25 (0.98–1.59) 0.074
Ethnicity
 Hispanic 15229 82 966 (742–1191) 17998 88 909 (700–1118) 0.94 (0.70–1.27) 0.691 19271 103 1004 (788–1220) 1.04 (0.78–1.39) 0.796
 Non-Hispanic/Unknown 230185 2803 904 (870–939) 246450 3145 993 (958–1029) 1.10 (1.04–1.16) <0.001 252688 3048 942 (908–976) 1.04 (0.99–1.10) 0.117
Residence
 Urban 133426 1254 820 (774–866) 144677 1486 931 (883–979) 1.13 (1.05–1.22) 0.001 149765 1459 878 (832–923) 1.07 (0.99–1.15) 0.078
 Rural 111969 1631 990 (940–1039) 119752 1747 1059 (1008–1111) 1.07 (1.00–1.15) 0.048 122162 1689 1014 (964–1064) 1.02 (0.96–1.1) 0.489
 Unknown 19 0 19 0 32 3
Body Mass Index (BMI)
 Underweight (< 18.5) 2657 62 2767 (1652–3882) 2917 79 2983 (1943–4024) 1.08 (0.77–1.5) 0.657 3083 90 3698 (2663–4733) 1.34 (0.97–1.85) 0.079
 Normal (18.5 – 24.9) 58348 812 1137 (1049–1225) 60996 886 1251 (1160–1343) 1.1 (1–1.21) 0.048 61159 830 1178 (1088–1268) 1.04 (0.94–1.14) 0.474
 Overweight (25 – 29.9) 69965 919 788 (733–842) 73435 1039 882 (825–938) 1.12 (1.02–1.22) 0.013 73887 966 815 (760–870) 1.03 (0.95–1.13) 0.458
 Obese (≥ 30) 86322 909 818 (763–873) 92787 1034 918 (860–977) 1.12 (1.03–1.23) 0.011 94910 1047 885 (829–941) 1.08 (0.99–1.18) 0.083
 Missing 28122 183 1079 (914–1243) 34313 195 1166 (988–1344) 1.08 (0.88–1.32) 0.448 38920 218 1064 (910–1218) 0.99 (0.81–1.2) 0.889
Number of chronic conditions
 0–1 74824 154 572 (460–684) 88385 188 671 (547–795) 1.17 (0.95–1.45) 0.142 95797 247 731 (615–847) 1.28 (1.05–1.56) 0.017
 2–3 52237 119 481 (378–584) 54544 135 479 (381–576) 1 (0.78–1.27) 0.971 55873 154 517 (422–612) 1.08 (0.85–1.37) 0.553
 4–6 53398 282 526 (461–591) 54559 307 585 (516–654) 1.11 (0.95–1.31) 0.194 54825 305 521 (459–583) 0.99 (0.84–1.17) 0.919
 7+ 64955 2330 1546 (1417–1674) 66960 2603 1663 (1544–1782) 1.08 (1.02–1.14) 0.010 65464 2445 1680 (1547–1813) 1.09 (1.03–1.15) 0.004
a

Research-consented adult residents of the 9-county region on Jan 01 of 2019.

b

Research-consented adult residents of the 9-county region on Jan 01 of 2020.

c

Research-consented adult residents of the 9-county region on Jan 01 of 2021.