TABLE 2.
Deaths and Standardized Mortality Rates Attributed To COVID-19, Natural Causes, and Unnatural Causes By Demographic and Clinical Characteristics
| Characteristic | COVID-19 | COVID-19 | Non-COVID Causes | ||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2020 | 2021 | 2019 | 2020 | Mortality rate ratio (95% CI) 2020 vs 2019 | P value | 2021 | Mortality rate ratio (95% CI) 2021 vs 2019 | P value | |||||||||||
| Population | Deaths | Mortality rate per 100,000 person-years (95% CI) | Population | Deaths | Mortality rate per 100,000 person-years (95% CI) | Population | Deaths | Mortality rate per 100,000 person-years (95% CI) | Population | Deaths | Mortality rate per 100,000 person-years (95% CI) | Population | Deaths | Mortality rate per 100,000 person-years (95% CI) | |||||
| Total | 264448 | 177 | 52 (44–60) | 271959 | 219 | 66 (57–75) | 245414 | 2885 | 905 (871–939) | 264448 | 3056 | 939 (906–973) | 1.04 (0.99–1.09) | 0.151 | 271959 | 2932 | 879 (847–912) | 0.97 (0.92–1.02) | 0.266 |
| Sex | |||||||||||||||||||
| Males | 126224 | 85 | 60 (47–72) | 130111 | 116 | 79 (64–93) | 113350 | 1461 | 1084 (1028–1140) | 126224 | 1532 | 1088 (1033–1143) | 1.00 (0.93–1.08) | 0.920 | 130111 | 1511 | 1049 (996–1103) | 0.97 (0.90–1.04) | 0.370 |
| Females | 138224 | 92 | 47 (37–56) | 141848 | 103 | 55 (44–65) | 132064 | 1424 | 763 (722–804) | 138224 | 1524 | 819 (776–861) | 1.07 (1.00–1.15) | 0.060 | 141848 | 1421 | 749 (709–788) | 0.98 (0.90–1.06) | 0.620 |
| Age (January 1st of the year) | |||||||||||||||||||
| 18–39 | 103202 | 6 | 6 (1–10) | 106254 | 6 | 6 (1–10) | 93109 | 81 | 91 (71–111) | 103202 | 106 | 105 (85–125) | 1.15 (0.86–1.54) | 0.331 | 106254 | 124 | 119 (98–140) | 1.30 (0.98–1.72) | 0.064 |
| 40–49 | 38972 | 0 | 40193 | 5 | 12 (2–23) | 35007 | 72 | 208 (160–256) | 38972 | 85 | 219 (172–265) | 1.05 (0.77–1.44) | 0.752 | 40193 | 77 | 192 (149–235) | 0.92 (0.67–1.27) | 0.623 | |
| 50–59 | 41653 | 5 | 13 (2–24) | 41782 | 16 | 38 (20–57) | 40244 | 191 | 479 (411–547) | 41653 | 199 | 478 (412–545) | 1.00 (0.82–1.22) | 0.980 | 41782 | 191 | 457 (392–522) | 0.95 (0.78–1.17) | 0.646 |
| 60–69 | 39949 | 19 | 47 (25–69) | 41660 | 37 | 88 (60–117) | 37592 | 373 | 991 (890–1091) | 39949 | 401 | 998 (901–1096) | 1.01 (0.88–1.16) | 0.912 | 41660 | 409 | 977 (882–1072) | 0.99 (0.86–1.13) | 0.848 |
| 70–79 | 24494 | 34 | 138 (92–185) | 25699 | 51 | 195 (141–248) | 23432 | 561 | 2377 (2180–2573) | 24494 | 630 | 2559 (2359–2759) | 1.08 (0.96–1.21) | 0.203 | 25699 | 599 | 2319 (2134–2505) | 0.98 (0.87–1.10) | 0.678 |
| 80+ | 16178 | 113 | 695 (566–824) | 16371 | 104 | 636 (513–759) | 16030 | 1607 | 9981 (9491–10471) | 16178 | 1635 | 10062 (9572–10551) | 1.01 (0.94–1.08) | 0.819 | 16371 | 1532 | 9274 (8807–9740) | 0.93 (0.87–1.00) | 0.040 |
| Age groups | |||||||||||||||||||
| 18–64 | 205571 | 18 | 9 (5–13) | 210807 | 48 | 23 (16–29) | 188770 | 516 | 279 (254–303) | 205571 | 581 | 285 (262–308) | 1.02 (0.91–1.15) | 0.721 | 210807 | 579 | 276 (254–299) | 0.99 (0.88–1.12) | 0.896 |
| 65+ | 58877 | 159 | 270 (228–312) | 61152 | 171 | 278 (236–320) | 56644 | 2369 | 4171 (4003–4339) | 58877 | 2475 | 4196 (4030–4362) | 1.01 (0.95–1.06) | 0.837 | 61152 | 2353 | 3833 (3678–3988) | 0.92 (0.87–0.97) | 0.004 |
| Race | |||||||||||||||||||
| White | 228005 | 160 | 49 (42–57) | 232660 | 204 | 65 (56–74) | 212305 | 2721 | 905 (870–940) | 228005 | 2862 | 930 (895–965) | 1.03 (0.98–1.08) | 0.306 | 232660 | 2738 | 871 (837–904) | 0.96 (0.91–1.01) | 0.156 |
| African American | 10826 | 7 | 139 (30–247) | 11641 | 4 | 121 (0–258) | 9267 | 49 | 937 (620–1253) | 10826 | 59 | 1063 (733–1392) | 1.13 (0.78–1.66) | 0.514 | 11641 | 59 | 912 (645–1179) | 0.97 (0.67–1.42) | 0.891 |
| Other/Unknown | 25617 | 10 | 69 (22–115) | 27658 | 11 | 64 (22–106) | 23842 | 115 | 753 (611–896) | 25617 | 135 | 952 (777–1128) | 1.26 (0.99–1.62) | 0.065 | 27658 | 135 | 877 (713–1041) | 1.16 (0.91–1.49) | 0.231 |
| Ethnicity | |||||||||||||||||||
| Hispanic | 17998 | 3 | 27 (0–59) | 19271 | 13 | 112 (48–176) | 15229 | 82 | 966 (742–1191) | 17998 | 85 | 882 (675–1088) | 0.91 (0.67–1.24) | 0.554 | 19271 | 90 | 892 (686–1099) | 0.92 (0.68–1.25) | 0.601 |
| Non-Hispanic/Unknown | 246450 | 174 | 52 (44–60) | 252688 | 206 | 63 (55–72) | 230185 | 2803 | 904 (870–939) | 246450 | 2971 | 941 (906–976) | 1.04 (0.99–1.10) | 0.128 | 252688 | 2842 | 879 (846–912) | 0.97 (0.92–1.02) | 0.283 |
| Residence | |||||||||||||||||||
| Urban | 144677 | 67 | 40 (31–50) | 149765 | 82 | 50 (39–61) | 133426 | 1254 | 820 (774–866) | 144677 | 1419 | 890 (843–937) | 1.09 (1.01–1.17) | 0.034 | 149765 | 1377 | 828 (784–872) | 1.01 (0.94–1.09) | 0.806 |
| Rural | 119752 | 110 | 62 (51–74) | 122162 | 137 | 82 (68–96) | 111969 | 1631 | 990 (940–1039) | 119752 | 1637 | 997 (947–1047) | 1.01 (0.94–1.08) | 0.834 | 122162 | 1552 | 932 (884–980) | 0.94 (0.88–1.01) | 0.090 |
| Unknown | 19 | 0 | 32 | 19 | 0 | 19 | 32 | ||||||||||||
| Body Mass Index (BMI) | |||||||||||||||||||
| Underweight (< 18.5) | 2917 | 2 | 98 (0–263) | 3083 | 3 | 80 (0–181) | 2657 | 62 | 2767 (1652–3882) | 2917 | 77 | 2886 (1858–3913) | 1.04 (0.75–1.46) | 0.806 | 3083 | 87 | 3619 (2588–4649) | 1.31 (0.94–1.81) | 0.107 |
| Normal (18.5 – 24.9) | 60996 | 42 | 50 (34–66) | 61159 | 44 | 61 (41–80) | 58348 | 812 | 1137 (1049–1225) | 60996 | 844 | 1202 (1112–1292) | 1.06 (0.96–1.16) | 0.260 | 61159 | 786 | 1117 (1030–1205) | 0.98 (0.89–1.08) | 0.727 |
| Overweight (25 – 29.9) | 73435 | 60 | 51 (37–65) | 73887 | 62 | 50 (37–63) | 69965 | 919 | 788 (733–842) | 73435 | 979 | 831 (776–886) | 1.05 (0.96–1.15) | 0.247 | 73887 | 904 | 765 (712–818) | 0.97 (0.89–1.06) | 0.534 |
| Obese (≥ 30) | 92787 | 61 | 56 (41–70) | 94910 | 91 | 76 (59–93) | 86322 | 909 | 818 (763–873) | 92787 | 973 | 862 (806–919) | 1.05 (0.96–1.15) | 0.251 | 94910 | 956 | 809 (755–862) | 0.99 (0.90–1.08) | 0.813 |
| Number of chronic conditions | |||||||||||||||||||
| 0–1 | 88385 | 6 | 24 (3–45) | 95797 | 24 | 80 (41–119) | 74824 | 154 | 572 (460–684) | 88385 | 182 | 647 (525–769) | 1.13 (0.91–1.40) | 0.258 | 95797 | 223 | 651 (541–760) | 1.14 (0.93–1.40) | 0.217 |
| 2–3 | 54544 | 9 | 32 (6–57) | 55873 | 14 | 35 (15–55) | 52237 | 119 | 481 (378–583) | 54544 | 126 | 447 (353–541) | 0.93 (0.72–1.19) | 0.567 | 55873 | 140 | 482 (389–575) | 1.00 (0.79–1.28) | 0.980 |
| 4–6 | 54559 | 17 | 35 (17–53) | 54825 | 26 | 39 (24–55) | 53398 | 282 | 526 (461–591) | 54559 | 290 | 550 (483–617) | 1.05 (0.89–1.23) | 0.591 | 54825 | 279 | 482 (422–542) | 0.92 (0.78–1.08) | 0.303 |
| 7+ | 66960 | 145 | 68 (50–85) | 65464 | 155 | 95 (71–119) | 64955 | 2330 | 1546 (1417–1674) | 66960 | 2458 | 1595 (1477–1713) | 1.03 (0.98–1.09) | 0.278 | 65464 | 2290 | 1585 (1454–1716) | 1.03 (0.97–1.09) | 0.391 |