Fig. 3.

Adjusted number of on-demand HAE attack medication doses administered per month from baseline to 26 months of active berotralstat treatment for patients who entered Part 2 of APeX-J (n = 17). Mean (SEM) values for the A.All 150 mg group and B.All 110 to 150 mg group. Baseline rates are based on medication use during the run-in period before study entry and are adjusted for the length of a month. For patients who received berotralstat following placebo, months are adjusted according to the date of the first berotralstat dose. BL, baseline; HAE, hereditary angioedema; SEM, standard error of the mean