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. 2024 Mar 6;8:27. doi: 10.1186/s41747-024-00429-1

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Example OE-MRI parametrical maps of thyroid gland (patient number 5). T1 weighted VIBE image is shown with overlaid parametric ΔT1 map of the thyroid gland (a, d, axial and coronal plane respectively) and overlaid statistical map of ΔT1 times (b, e). Blue colour indicates statistically significant decrease in T1 times, white indicates no statistically significant change, and red indicates statistically significant increasing T1 times. c Time series of T1 times averaged over the entire thyroid VOI. f Histogram of ΔT1 times for the entire thyroid VOI. OE-MRI Oxygen-enhanced magnetic resonance imaging, VIBE Volumetric interpolated breath-hold examination, VOI Volume of interest