Table 2.
LDL-C levels estimated by the equations in each cohort.
| LDL-C (mmol/L) | Total population (n = 2445) | P value | Cohort 1 (n = 1497) | P value | Cohort 2 (n = 748) | P value |
|---|---|---|---|---|---|---|
| LDL-CDM | 3.10 ± 1.07 | – | 3.10 ± 1.07 | – | 3.09 ± 1.06 | – |
| LDL-CD | 3.09 ± 1.08 | 0.146 | 3.09 ± 1.09 | 0.105 | 3.09 ± 1.06 | 0.912 |
| LDL-CF | 2.83 ± 1.14 | < 0.001 | 2.83 ± 1.14 | < 0.001 | 2.85 ± 1.12 | < 0.001 |
| LDL-CM | 2.94 ± 1.16 | < 0.001 | 2.94 ± 1.12 | < 0.001 | 2.95 ± 1.09 | < 0.001 |
| LDL-CS | 2.92 ± 1.12 | < 0.001 | 2.91 ± 1.13 | < 0.001 | 2.93 ± 1.11 | < 0.001 |
Values presented as mean ± SD. P values are of paired t-test between direct LDL-C and LDL-C estimated by each equation. LDL-CDM, directly measured low-density lipoprotein cholesterol, LDL-CD, novel equation-derived LDL-C, LDL-CF, LDL-C calculated by Friedewald equation, LDL-CM, LDL-C calculated by Martin–Hopkins equation, LDL-CS, LDL-C calculated by Sampson-NIH equation.