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. 2024 Mar 5;4:39. doi: 10.1038/s43856-024-00465-3

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 2 — a WD+CCl4 mouse model vs. Control, b human MASH vs. Control, c human MASH F3 vs. MASLD (MASH progression). d Corresponding Venn diagram of the statistically significant (FDR < 0.05) altered pathways across the three datasets. Number labels on the left panels (a, b, c) correspond to the pathways as indicated in the table on the right. WD+CCl4: Western diet supplemented by carbon tetrachloride, MASLD: Metabolic dysfunction-associated steatotic liver, MASH: Metabolic dysfunction-associated steatohepatitis.