Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2024 Mar 5;4:39. doi: 10.1038/s43856-024-00465-3

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 4 — a High-resolution respirometry of oxygen consumption (O2 flux) in mitochondria in liver homogenates of control vs. WD+CCl4 group. b Immunoblot showing expression of mitochondrial pyruvate carrier MPC1 and MPC2 in liver homogenates. Vinculin served as the loading control. Both MPC1 and MPC2 were lower in WD+CCl4 vs. the control group. (unpaired t-test; *p < 0.05; **p < 0.005; ***p < 0.001). c fatty acid oxidation was measured by high-resolution respirometry of oxygen consumption (O2 flux) in mitochondria in liver homogenates of the control vs. WD+CCl4 group. d Immunoblot showing expression of carnitine palmitoyltransferase CPT1α and CPT2 in liver homogenates. Vinculin served as the loading control. CPT-2 was lower in WD+CCl4 vs. the control group. (unpaired t-test; *p < 0.05). All box plot error bars represent standard deviation. WD+CCl4: Western diet supplemented by carbon tetrachloride. (a: WD+CCl4 n = 7, control n = 5, b, d: WD+CCl4 n = 5, control n = 5, c: WD+CCl4 n = 6, control n = 4).