Table 5.
Univariate hazard ratios for melanoma recurrence and death of positive SLN patients (N = 19)
| Prognostic factors | Recurrence factor | Survival factor | ||
|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | |
| CLND (yes vs no) | 1.98 (0.28–14.2) | 0.35 | 0.52 (0.03–8.32) | 0.64 |
| Age at diagnosis | ||||
| (≥ 10 years vs < 10 years) | 0.76 (0.09–6.5) | 0.8 | –a | |
| Primary tumor location | ||||
| Trunk vs extremity | 0.51 (0.06–4.63) | 0.55 | –a | |
| Head or neck vs extremity | 0.9 (0.09–9.5) | 0.93 | –a | |
| Sex | ||||
| (Male vs female) | 1.88 (0.48–7.38) | 0.37 | 1.45 (0.13–16.3) | 0.76 |
| Ulceration | ||||
| (Yes vs no) | 1.63 (0.46–5.81) | 0.45 | 0.47 (0.04–5.24) | 0.54 |
| Median tumor depth (range) | 1.12 (0.86–1.47) | 0.38 | –a | |
| Margin statusc (vs 10 mm) | ||||
| < 5 mm | 0.37 (0.03–4.13) | 0.42 | –a | |
| ≥ 5 mm to < 10 mm | – | – | ||
| Mitotic counts | ||||
| (presence vs absence) | 0.37 (0.04–3.17) | 0.36 | –a | |
aThe samples were too small to analyze HR
bMargin status indicates the size of the resection margin
CI confidence interval, CLND complete lymph node dissection, CM conventional melanoma, HR hazard ratio, neg negative, pos positive, Q quartile, SD standard deviation, SLN sentinel lymph node