Table 6.
Characteristics of the four patients with pediatric melanoma who died
| # | Characteristic | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Sex, age at Dx (years) | Histology | Primary tumor location | Tumor stage | SLNB (status) | CLND (result) | Margin (mm) | Mitototic counta | Genomics | Time to deathb (months) | |
| 1 | M, 13 | Nodular | Truncal | T2a | Pos (1/2), subcapsular | N | Free | 3 | n/a | 37 |
| 2 | F, 16 | Melanoma | Truncal | T3a | Pos (2/5), subcapsular | Y (neg) | 0.5 | 3 | n/a | 96 |
| 3 | M, 14 | Superficial spreading | Truncal | T2b | Pos (1/1), extracapsular | Y (neg) | 7 | 5 | BRAF | 17 |
| 4 | F, 13 | Folliculocentric | Head/neck | T4a | neg, 0/5 | N | 8 | > 20 | BRAF and P16 deletion | 6 |
aMitotic counts indicate number of mitosis per mm2
bTime to death indicates the period from diagnosis to mortality
CLND complete lymph node dissection, Dx diagnosis, F female, M male, pos positive, N no, neg negative, Pt No. patient number, SLNB sentinel lymph node biopsy