Table 2.
Summary of heterogeneity and multiplicity results
| Outcomes | Cochran’s Q | PCochran’s Q | MR Egger intercept | PMR Egger intercept | Global test RSSobs | PGlobal |
|---|---|---|---|---|---|---|
| Excessive, frequent and irregular menstruation | 8.552 | 0.931 | -9.90 × 10− 05 | 0.728 | 10.748 | 0.929 |
| abnormal uterine and vaginal bleeding | 12.35 | 0.720 | -1.45 × 10− 04 | 0.363 | 13.946 | 0.817 |
| Endometriosis | 21.905 | 0.146 | -2.26 × 10− 04 | 0.110 | 26.495 | 0.135 |
| Female infertility | 9.479 | 0.892 | -1.12 × 10− 04 | 0.189 | 11.418 | 0.917 |
| Hemorrhage in early pregnancy | 10.44 | 0.843 | -1.63 × 10− 04 | 0.072 | 11.935 | 0.872 |
| Other abnormal products of conception | 26.79 | 0.044 | -4.40 × 10− 05 | 0.751 | 30.194 | 0.071 |
| Number of spontaneous miscarriages | 14.601 | 0.554 | 3.94 × 10− 03 | 0.241 | 17.801 | 0.524 |
| Single spontaneous delivery | 19.205 | 0.258 | -1.25 × 10− 04 | 0.378 | 26.243 | 0.119 |
| Long labour | 8.981 | 0.914 | 1.99 × 10− 04 | 0.065 | 11.093 | 0.911 |
| Birth weight of first child | 10.066 | 0.863 | 8.78 × 10− 04 | 0.698 | 23.116 | 0.265 |
Abbreviations: RSSobs [observed residual sum of squares]