Table 2.
Uni- and multivariate cox regression analyses of the main composite endpoints across the PNI
| Characteristics | Univariate cox regression analysis | Multivariate cox regression analysis | ||||
|---|---|---|---|---|---|---|
| Hazard ratio | 95% CI | P value | Hazard ratio | 95% CI | P value | |
| Age | 1.052 | 1.032–1.072 | < 0.001 | 1.034 | 1.008–1.059 | 0.009 |
| Sex | 1.152 | 0.787–1.687 | 0.467 | – | – | – |
| Height | 0.994 | 0.972–1.017 | 0.621 | – | – | – |
| Weight | 1.006 | 0.990–1.022 | 0.485 | – | – | – |
| BMI | 1.042 | 0.987–1.101 | 0.139 | – | – | – |
| Hypertension | 1.462 | 0.946–2.260 | 0.087 | – | – | – |
| Diabetes | 1.775 | 1.232–2.557 | 0.002 | 1.732 | 1.186–2.527 | 0.004 |
| Smoking | 0.853 | 0.638–1.141 | 0.284 | – | – | – |
| Drinking | 0.635 | 0.376–1.074 | 0.091 | – | – | – |
| MI type | 1.139 | 0.793–1.634 | 0.482 | – | – | – |
| Killip classification | 1.351 | 1.151–1.586 | < 0.001 | 1.093 | 0.908–1.315 | 0.349 |
| Hemoglobin | 0.982 | 0.974–0.991 | < 0.001 | 0.997 | 0.987–1.008 | 0.605 |
| ALT | 1.001 | 1.000–1.001 | < 0.001 | 1.000 | 1.000–1.001 | 0.457 |
| eGFR | 0.982 | 0.975–0.989 | < 0.001 | 0.998 | 0.987–1.009 | 0.746 |
| Total cholesterol | 0.859 | 0.715–1.032 | 0.105 | – | – | – |
| Triglyceride | 0.848 | 0.699–1.029 | 0.096 | – | – | – |
| LDL | 0.794 | 0.630–1.001 | 0.051 | – | – | – |
| HDL | 1.133 | 0.647–1.985 | 0.662 | – | – | – |
| sUA | 1.003 | 1.001–1.005 | < 0.001 | 1.002 | 1.000–1.004 | 0.091 |
| cTNT | 1.092 | 1.038–1.149 | 0.001 | 1.050 | 0.992–1.111 | 0.091 |
| PNI type | 2.300 | 1.538–3.441 | < 0.001 | 1.674 | 1.076–2.604 | 0.022 |
BMI body mass index, MI myocardial infarction, ALT alanine aminotransferase, HDL high density lipoprotein, LDL low density lipoprotein, eGFR estimated glomerular filtration rate, sUA serum uric acid, CKMB creatine kinase myocardial band, CTNT cardiac troponin T, PNI prognostic nutritional index, CI confidence interval