Table 4.
Types of epilepsy | Animal models | Methods inducing epilepsy |
Related neural circuits | References |
---|---|---|---|---|
MTLE | Male Sprague–Dawley rats | Methionine sulfoximine (2.5 mg/mL) | GABAergic neurotransmission | Dhaher et al. (2021) |
Autosomal dominant sleep-related hypermotor epilepsy | S286L-TG rats | Transmission abnormalities of L-glutamate and GABA in the thalamocortical pathway | Fukuyama et al. (2020b) | |
Autosomal dominant sleep-related hypermotor epilepsy | S286L-TG rats | Transmission in the RTN–MDTN–OFC pathway associated with connexin hemichannel | Fukuyama et al. (2020a) | |
Epilepsy | Thy1-ChR2 rats | Optogenetic stimulation | Acquired hyperexcitable circuit | Shimoda et al. (2022) |