Table 4.
Subgroup analyses of the relationship between PHR values and the prevalence of nephrolithiasis.
| Characteristics | T1 (< 15.32) | T2 (15.32–21.36) | T3 (21.36–183.52) | P for trend | P for interaction |
|---|---|---|---|---|---|
| Age (years) | 0.071 | ||||
| <45 | ref | 1.339(0.990,1.811) | 1.884(1.456,2.439) | <0.0001 | |
| 45-64 | ref | 1.296(1.053,1.595) | 1.535(1.244,1.893) | <0.0001 | |
| >=65 | ref | 1.356(1.074,1.712) | 1.242(1.004,1.536) | 0.015 | |
| Sex | 0.672 | ||||
| Male | ref | 1.205(0.996,1.458) | 1.298(1.075,1.567) | 0.008 | |
| Female | ref | 1.147(0.913,1.442) | 1.394(1.144,1.699) | 0.001 | |
| Race | 0.278 | ||||
| Mexican American | ref | 0.933(0.658,1.322) | 1.004(0.719,1.402) | 0.91 | |
| Non-Hispanic Black | ref | 1.047(0.772,1.418) | 1.008(0.726,1.401) | 0.945 | |
| Non-Hispanic White | ref | 1.253(1.042,1.507) | 1.476(1.248,1.746) | <0.0001 | |
| Other race | ref | 1.332(0.968,1.833) | 1.592(1.201,2.110) | 0.002 | |
| Education level | 0.4 | ||||
| Less than high school | ref | 1.070(0.723,1.584) | 1.511(1.012,2.257) | 0.038 | |
| High school | ref | 1.098(0.881,1.369) | 1.187(0.975,1.444) | 0.085 | |
| More than high school | ref | 1.280(1.044,1.570) | 1.491(1.217,1.827) | <0.001 | |
| Marital status | 0.96 | ||||
| Married | ref | 1.240(1.031,1.491) | 1.447(1.212,1.727) | <0.0001 | |
| Live separated | ref | 1.208(0.929,1.572) | 1.318(1.073,1.619) | 0.009 | |
| Never married | ref | 1.264(0.860,1.857) | 1.347(0.920,1.971) | 0.121 | |
| Family PIR | 0.068 | ||||
| < 1 | ref | 1.232(0.929,1.633) | 1.766(1.382,2.257) | <0.0001 | |
| 1-3 | ref | 1.037(0.851,1.263) | 1.171(0.971,1.414) | 0.093 | |
| > 3 | ref | 1.400(1.100,1.782) | 1.567(1.240,1.980) | <0.001 | |
| BMI (kg/m^2) | 0.919 | ||||
| <30 | ref | 1.157(0.865,1.548) | 1.180(0.841,1.655) | 0.261 | |
| >=30 | ref | 1.098(0.929,1.297) | 1.201(1.032,1.397) | 0.016 | |
| Smoking status | 0.484 | ||||
| Never | ref | 1.221(0.993,1.501) | 1.433(1.191,1.725) | <0.001 | |
| Former | ref | 1.362(1.080,1.717) | 1.369(1.056,1.775) | 0.015 | |
| Now | ref | 0.978(0.674,1.420) | 1.285(0.980,1.686) | 0.036 | |
| Alcohol usage | 0.566 | ||||
| Never | ref | 0.993(0.645,1.529) | 1.165(0.704,1.927) | 0.546 | |
| Former | ref | 1.153(0.804,1.653) | 1.245(0.890,1.740) | 0.202 | |
| Moderate | ref | 1.134(0.835,1.539) | 1.555(1.139,2.122) | 0.008 | |
| Heavy | ref | 1.448(0.975,2.152) | 1.897(1.295,2.781) | 0.001 | |
| DM | 0.481 | ||||
| No | ref | 1.142(0.961,1.357) | 1.295(1.092,1.536) | 0.003 | |
| Yes | ref | 1.357(1.058,1.741) | 1.324(1.036,1.692) | 0.054 | |
| Hypertension | 0.821 | ||||
| No | ref | 1.167(0.946,1.441) | 1.340(1.107,1.623) | 0.003 | |
| Yes | ref | 1.265(1.048,1.525) | 1.363(1.137,1.633) | 0.001 | |
| Hyperlipidemia | 0.349 | ||||
| No | ref | 1.237(0.976,1.568) | 1.041(0.727,1.491) | 0.415 | |
| Yes | ref | 1.159(0.979,1.373) | 1.262(1.088,1.463) | 0.002 | |
| CKD | 0.005 | ||||
| No | ref | 1.117(0.946,1.318) | 1.327(1.143,1.539) | <0.001 | |
| Yes | ref | 1.862(1.466,2.365) | 1.757(1.304,2.368) | <0.001 | |
| CHD | 0.548 | ||||
| No | ref | 1.198(1.031,1.391) | 1.392(1.206,1.606) | <0.0001 | |
| Yes | ref | 1.523(0.997,2.328) | 1.460(0.937,2.274) | 0.073 |
PHR, platelet/high-density lipoprotein cholesterol ratio; BMI, body mass index; PIR, poverty income ratio; DM, diabetes mellitus; CKD, chronic kidney disease; CHD, coronary heart disease; OR, odds ratio; CI confidence interval; Ref, reference.