Table 2.
Associations between tertile of estradiol (reference: <3.68 pg./mL) and CREAD/DSST/AFS test score, β (95%CI) p-value.
| Estradiol (pg/mL) | Tertile of estradiol | p for trend | ||
|---|---|---|---|---|
| T1 (<3.68) | T2 (≥3.68to ≤ 7.49) | T3 (>7.49) | ||
| CERAD test | ||||
| Crude | 1.00 (Ref.) | 0.13 (−0.29, 0.56) 0.5309 | 0.23 (−0.20, 0.66) 0.2889 | 0.02 (−0.02, 0.07) 0.3048 |
| Model 1 | 1.00 (Ref.) | −0.10 (−0.51, 0.32) 0.6464 | 0.05 (−0.37, 0.47) 0.8185 | 0.01 (−0.04, 0.05) 0.7144 |
| Model 2 | 1.00 (Ref.) | −0.06 (−0.48, 0.36) 0.7885 | 0.02 (−0.45, 0.49) 0.9364 | 0.00 (−0.05, 0.06) 0.8836 |
| DSST test | ||||
| Crude | 1.00 (Ref.) | 3.89 (0.89, 6.89) 0.0113 | 5.15 (2.11, 8.18) 0.0009 | 0.52 (0.19, 0.85) 0.0021 |
| Model 1 | 1.00 (Ref.) | 0.82 (−1.76, 3.39) 0.5344 | 3.06 (0.44, 5.68) 0.0224 | 0.35 (0.06, 0.63) 0.0172 |
| Model 2 | 1.00 (Ref.) | 1.12 (−1.30, 3.55) 0.3648 | 0.61 (0.87, 6.34) 0.0099 | 0.40 (0.11, 0.70) 0.0079 |
| AFS test | ||||
| Crude | 1.00 (Ref.) | 0.27 (−0.68, 1.22) 0.5751 | 0.95 (−0.01, 1.91) 0.0535 | 0.11 (0.00, 0.21) 0.0460 |
| Model 1 | 1.00 (Ref.) | −0.39 (−1.29, 0.52) 0.4028 | 0.52 (−0.39, 1.44) 0.2636 | 0.07 (−0.03, 0.17) 0.1495 |
| Model 2 | 1.00 (Ref.) | −0.15 (−1.03, 0.74) 0.7454 | 0.80 (−0.19, 1.80) 0.1142 | 0.10 (−0.01, 0.21) 0.0702 |
Model 1 adjusted for age, race. Model 2 adjusted for age, race, education, BMI, smoking, drinking, DM, sleeping disorder.