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. 2024 Feb 21;15:1358525. doi: 10.3389/fmicb.2024.1358525

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Copyright © 2024 Hu, Song, Zhang, Ruan, Li, Yu and Huang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of EA on motor functions in rotenone-induced PD rat. (A) EA on ST25 of PD rat treated with rotenone for 4 weeks (EA group). (B) Experimental schedule of the EA treatment in the rotenone-induced PD rats. All motor behavioral tests including (C) pole, and (D) rotarod tests were performed the ending day of the EA intervention (n = 6, Student t-test, ^* p < 0. 05, ^** p < 0. 01). (E) Immunohistostaining for tyrosine hydroxylase (TH) in the SN of brain extracted from Control, Model, and EA group and counts of TH⁺ neurons (n = 4. Scale bar: 100 μm). W, week.