Table 2.

Univariable and multivariable analysis of factors associated with the USAP value as a continuous variable in linear regression analysis

Parameter	Univariable analysis		Multiple regression analysis
	Pearson r	P-value	Estimatea)	Standard error	P-value
All patients (n=982)
Age (year)	-0.349	<0.001	-0.001	0.000	<0.001
Sexa)	0.074	0.021	0.004	0.005	0.008
BMI (kg/m2)	0.513	<0.001	0.002	0.001	0.020
SCD (mm)	0.461	<0.001	0.004	0.001	<0.001
MR elastography	-0.054	0.091	0.008	0.003	0.004
MRI-derived PDFF	0.731	<0.001	0.078	0.003	<0.001
MR elastography×MRI-derived PDFF	-0.186	<0.001	0.009	0.004	0.013
Patients without hepatic steatosis (grade S0, n=344)
Age (year)	-0.039	0.467	0.000	0.000	0.480
Sexa)	-0.015	0.788	-0.013	0.008	0.100
BMI (kg/m2)	0.240	<0.001	0.000	0.001	0.751
SCD (mm)	0.361	<0.001	0.006	0.001	<0.001
MR elastography	0.173	0.001	0.032	0.017	0.037
MRI-derived PDFF	0.084	0.122	0.061	0.021	<0.001
MR elastography×MRI-derived PDFF	-0.158	0.003	0.023	0.019	0.229
Patients with hepatic steatosis (grades S1-S3, n=638)
Age (year)	-0.341	<0.001	-0.001	0.000	0.002
Sexa)	0.057	0.154	0.006	0.006	0.317
BMI (kg/m2)	0.331	<0.001	0.002	0.001	0.094
SCD (mm)	0.285	<0.001	0.002	0.001	0.004
MR elastography	-0.088	0.034	0.002	0.003	0.482
MRI-derived PDFF	0.604	<0.001	0.061	0.001	<0.001
MR elastography×MRI-derived PDFF	0.001	0.227	0.014	0.005	0.007

Estimated value of coefficients.

Steatosis grade: S0, MRI-PDFF <5.2%; S1, 5.2≤MRI-PDFF<11.3%; S2, 11.3≤MRI-PDFF<17.1%; and S3, MRI-PDFF ≥17.1% [12].

USAP, ultrasound attenuation parameter; BMI, body mass index; SCD, skin-capsule distance; MR, magnetic resonance; MRI, magnetic resonance imaging; PDFF, proton density fat fraction.

^a)Female=0, male=1.