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. 2024 Mar 6;14(1):38. doi: 10.1038/s41408-024-01024-8

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 7 — A Comparison of PBM scores between MGUS patients who progressed to MM (P) and those who did not progressed (NP) to MM. PBM scores are significantly higher in the “P” group compared to the “NP” group. p values were calculated using the Wilcoxon rank-sum test. B Receiver operating characteristic (ROC) curve for predicting progression to MM using PBM scores. C Proportion of MGUS patients with progression exceeding the critical PBM threshold, determined individually for each patient. The dashed line represents the optimal PBM cutoff of 0.875 as derived from the ROC curve, with percentages indicating the rate of patients categorized into low and high PBM groups based on this cutoff. D Proportions of MGUS patients who progressed to MM in high and low PBM groups. p values are calculated using Fisher’s exact test.