Table 2.
Summary of the reported cases with rituximab treatment for GBS.
| References | Age | Gender | Causes of GBS | Clinical features | GBS therapy | Outcome |
|---|---|---|---|---|---|---|
| Gu et al. (17) | 49 | Female | Ipilimumab 3 mg/kg Nivolumab 1 mg/kg | Weakness and pain of the 4 limbs Sensory loss | (1) IVIg and steroids (2) Steroids, plasma exchange, mycophenolate, and rituximab | Significant improvement in nerve and muscle strength |
| Janssen et al. (3) | 74 | Male | Ipilimumab 10 mg/kg q3w | Tetraparesis Distal hypoesthesia of the 4 limbs Diffuse areflexia | (1) Steroids (2) IVIg and Infliximab (3) Plasmapheresis (4) IVIg and rituximab |
Fatal due to respiratory failure/pneumonia |
| Beshir et al. (18) | 69 | Male | Systemic lupus erythematosus | Severe generalized weakness diplopia and swallowing difficulty | (1) IVIg and steroids (2) rituximab plasma exchange |
No motor deficit Intermittent paraesthesia of the 4 limbs |
| Reddy (19) | 9 | Female | Systemic lupus erythematosus | Weakness and pain of the 4 limbs Sensory loss | (1) IVIg and steroids (2) rituximab |
Full recovery |
| Ostronoff et al. (8) | 58 | Male | Allogeneic hematopoietic SCT | Weakness and pain of the 4 limbs Facial palsy | (1) IVIg (2) rituximab | Significant muscle strength recovery |