Figure 7.

ANLN enhances proliferation and metastasis of PCa cells by regulating IGF2BP1. A, B. Result of EdU assay showing the cell proliferation in PC-3 and DU145 cells expressing the different constructs. ns P ≥ 0.05, ****P < 0.0001. C-E. Representative images and quantification of cell migration and invasion in DU145 and PC-3 cells were measured using transwell assays. ns P ≥ 0.05, *P < 0.05, ****P < 0.0001. F, G. Representative images of the wound-healing assays for prostate cancer cells expressing different vectors. ****P < 0.0001. Scale bar = 100 μm.